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Ongoing Research Studies

Ongoing Research Studies

The CARE program is supported by a research grant from the National Institutes of Health. The primary goal of the research is to identify risk factors for the later development of mental illness. Below are the CARE Program’s ongoing research studies.

 For more information and to find out how to participate in our research, contact: (619) 543-1851

Benefits of Research

  • All participants undergo a clinical evaluation and neuropsychological assessment.
  • Referral services and case management, of necessary.
  • Eligible participants are compensated for their time.
  • Participants in neuroimaging studies will receive a clinical read if indicated.
  • Research participation may help contribute to the understanding and treatment of young people with mental health concerns in the future.

Eligibility Criteria

  • Ages 12-35 years
  • Individuals with changes in mood, behavior, or thought patterns, unusual behaviors and social withdrawal, without experiencing a psychotic episode


  • Ages 12-35 years
  • People who have experienced a psychotic episode within the past two years, preferably medication naïve.


Clinical Trials

Researchers want to compare the efficacy and safety of the study medications, given by injection or as pills, in patients recently diagnosed with Schizophrenia and Schizophreniform disorder.

Psychosocial and Treatment Studies

Our psychosocial and treatment studies range from 6-18 weeks of group therapy. Depending on study topics covered may include: Improving concentration, learning, memory and problem-solving abilities, conversational skills, recreational activities, learning and practicing mindfulness skills, coping with unhelpful thoughts and changes in mood, enhancing social skills and understanding changes in mood, psychological and social functioning. 


Progresar is a study being conducted by the UCSD CARE program in collaboration with the Instituto Nacional de Neurología y Neurocirgía (INNN) in Mexico City, Mexico. This study is looking at the effects of group therapy on cognitive functioning.

Este estudio también se conduce en el Instituto Nacional de Neurología y Neurocirugía (INNN) en la cuidad de México, México. Visite la página web de INNN.

Progresar Flyer: English | Español



The "ReGroup" study is currently being conducted by the UCSD CARE program in collaboration with Zucker Hillside Hospital and the University of Calgary, and aims to find out more about the effects of group therapy on functioning.

Regroup Flyer: ReGroup

Biomarker and Neuroimaging Studies

Biomarker and neuroimaging studies aim to understand how measures of brain structure and functioning, as well as biological markers relate to clinical symptoms. These studies collect different biological markers taken from, blood samples, saliva samples, urine samples, and MRIs. The relationship between these measures and clinical symptoms are assessed and analyzed to learn more about identifying the risk of developing mental illness.

Learn more about one of our biomarker and neuroimaging studies, the North American Prodrome Longitudinal Study (NAPLS). 

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